Protocol curvesSteady-state testosterone modelling

Tap or drag the chart to read a point
Response factorScales curves for individual absorption. 1.0 is average.
Vial concentrationmg/mL. Sets per-shot volume and syringe units.

First-order absorption into one compartment. Effective half-life 4.5 days for both esters — once hydrolysed they release the identical testosterone molecule, so elimination is the same and only the depot differs. Release half-life 0.6 days IM / 2.0 days SubQ for cypionate, 0.5 / 1.7 for enanthate, which also carries 3% more testosterone per milligram by molecular weight. Calibrated so a single 200 mg IM dose peaks near 920 ng/dL on day 2.

Both routes are given identical bioavailability, so differences shown are depot smoothing alone. Real absorption rate, SHBG, aromatase activity and assay method move actual numbers far more than the differences between adjacent protocols here — and far more than the gap between the two esters, which head-to-head studies have generally found clinically indistinguishable. Shapes are the point; treat absolute values as illustration.